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Discovery and Structure-Activity Relationships of A Series of Pyroglutamic Acid Amide Antagonists of the P2x(7) Receptor

Muna H. Abdi,Paul J. Beswick,Andy Billinton,Laura J. Chambers,Andrew Charlton,Sue D. Collins,Katharine L. Collis,David K. Dean,Elena Fonfria,Robert J. Gleave,Clarisse L. Lejeune,David G. Livermore,Stephen J. Medhurst,Anton D. Michel,Andrew P. Moses,Lee Page,Sadhana Patel,Shilina A. Roman,Stefan Senger,Brian Slingsby,Jon G. A. Steadman,Alexander J. Stevens,Daryl S. Walter

Bioorganic & Medicinal Chemistry Letters（2010）

引用 71|浏览64
关键词
P2X7,Antagonist,Pain,SAR
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