Coexistent hemophilia A and idiopathic thrombocytopenic purpura

routine manner with CSF have generally overestimated glucose va lues . : Swietek and associates ~ modified the technique to improve the accuracy of CSF determinations with Dextrostix. Unfortunately, their method was time consuming and cumbersome. Accuracy of this modification of the Dextrostix technique is dependent upon several critical factors including: quality control of the Dextrostix reagent sirips; frequent calibration of the reflectometer (at least twice daily); adequate sample size to completely cover the tip of the reagent strip; and strict adherence to the 45-second incubation period. Dextrostix-45 values were consistent with those obtained by the reference glucose oxidase method over a glucose concentration range of 10 to 160 mg/d l and a protein range of 11 to 1,000 mg/d l . These values are well within the scope of those commonly encountered in CSF analysis. Therefore, it is suggested that the use of Dextrostix with a 45-second incubation period and the reflectometer may provide a rapid and accurate bedside estimation of CSF glucose. R E F E R E N C E S