慢性肾衰竭患者听力损失相关因素探讨
Fujian Medical Journal(2005)
Abstract
目的探讨慢性肾功能衰竭(CRF)患者听力损失与血清C反应蛋白(CRP)、甲状旁腺激素(PTH)及血肌酐(SCr)之间的相关性。方法检测30例CRF的CRP、PTH和SCr,并进行纯音听阈测定,评价在各频率的气导阈值,以语言频率作为结果变量,用直线回归法分析气导听力损失与患者血清CRP、PTH及SCr之间的相关性。结果CRF患者气导听力在各频率均较对照组有显著下降,且在高频更明显。CRF患者听力频率听阈与血CRP、PTH、SCr呈正相关。结论CRF患者的听力损伤不仅与肾功能损伤程度及血中PTH增高有关,而且与机体的微炎症态度有关。
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Key words
Chronic renal failure,Hearing loss,Microinflammatory state
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