Impaired coronary vasodilation with Regadenoson in patients with angiographically normal coronaries when compared to normal volunteers - Insights from Quantitative MRI Perfusion

Quantitative myocardial perfusion to assess impaired coronary vasoreactivity has been used to identify subclinical atherosclerosis. Impaired coronary vasodilation has been observed in patients with cardiac risk factors in the MESA cohort. The coronary vasodilator response in patients with angiographically normal coronary arteries/minimal stenosis is not known. The purpose of this study was to compare the stress myocardial blood flow (MBF) of patients with normal coronaries/minimal stenosis with normal volunteers.