Phenylketonuria: white-matter changes assessed by 3.0-T magnetic resonance (MR) imaging, MR spectroscopy and MR diffusion Fenilchetonuria: studio RM a 3,0 T delle alterazioni della sostanza bianca con imaging di base, di spettroscopia e di diffusione
Radiologia Medica(2009)
Abstract
Purpose. This study evaluated the sensitivity of a 3.0-Tesla (T) magnetic resonance imaging (MRI) in measuring cerebral phenylalanine using proton magnetic resonance spectroscopy and in assessing MR-documented white- matter changes by means of diffusion studies (diffusion- weighted imaging, apparent diffusion coefficient map; diffusion tensor imaging) in patients with phenylketonuria. Materials and methods. Thirty-two patients with the
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