Linfoma subcutâneo de células T tipo paniculíte - A propósito de um caso clínico

Marisa Antunes,Bruno Grima, Alexandra Chaveiro,Cândida Fernandes, Albertina Nunes, Ana Afonso,Maria Gomes,Nuno Riso,Vaz Riscado

msra

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摘要
T cell cutaneous lymphoma (T.C.C.L.), panni- culitis type, is a rare malignancy of postthymic T cells. A clinical case of a twenty-three year old, female patient, with a five-year evolution of recurret subcutaneous nodules and, later on, hepatosplenomegaly and fever is presented. The diagnosis was only possible with repeated cutaneous byopsies and in late stage of the disease. The patient died following a fatal and rapid leukemia transformation of the lympho- ma. Often, the histological aspects of the skin,in early stages of T.C.C.L., does not reveal malig- nant characteristics. The diagnosis is frequently delayed due to lack of symptoms and dubious hystology, contribuing to the late institution of therapy. The differential diagnosis of T.C.C.L. is established with cutaneous manifestations
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关键词
requiring sofisticated laborato- rial techniques such as skin,erythema nodosum,panni- culitis,of autoimmune diseases and end-stage blastic nk lymphoma,bone marrow and peripheral blood immunophenotyping. key words: subcutaneous lymphoma
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