系统性红斑狼疮患者血清IL-10、IL-12和sFas水平及其临床意义
Journal of Tropical Medicine(2007)
Abstract
目的探讨系统性红斑狼疮(SLE)患者血清白细胞介素10(IL-10)、白细胞介素12(IL-12)和可溶性Fas(sFas)水平及其临床意义。方法采用酶联免疫夹心(ELISA)法检测22例SLE患者和20例正常人血清IL-10、IL-12和sFas水平。结果与正常对照组比较,SLE患者IL-10和sFas水平明显升高(P<0.01);IL-12水平有下降趋势,但差异无统计学意义(P>0.05)。结论IL-10、IL-12和sFas与SLE免疫发病机制密切相关。
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Key words
soluble Fas,interleukin 12,systemic lupus erythematosus,interleukin 10
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