368 THE FATTY LIVER IN NON OBESE CITIZEN: PRELIMINARY RESULTS FROM A LARGE OSSERVATIONAL STUDY (BAGNACAVALLO STUDY)
Journal of hepatology(2010)
Abstract
Patients with self declared excessive alcohol consumption (above 20g/day for males, 10g/day for females) have been excluded.NAFLD was evaluated according to Brunt's score, while histology activity index (HAI) and fibrosis stage for CHB were estimated using Knodell score.The patients were divided in 2 groups: CHB patients without steatosis (n = 61) and with steatosis (n = 59).Results: Out of 120 patients with CHB (male/female = 76/44, median age = 40.41),49.15% had steatosis.No statistically significant differences among HAI and the aminotransferase levels was found between the two groups (p = 0.320 and p = 0.128).The presence of NAFLD associated with CHB was significantly correlated with age (p = 0.001), MS (p = 0.051) and the degree of hepatic fibrosis (F ≥ 2) (p = 0.001).In patients with CHB and steatosis, significant correlations between female sex and the presence of MS (p = 0.007) as well as between HAI and age (p = 0.003) were found.Conclusions: NAFLD was detected in 49.16% of patients with CHB.A positive correlation with age, MS (obesity, diabetes mellitus and/or dislipidemia) and the fibrosis stage was observed.No significant correlations between NAFLD and the aminotransferase levels were found.
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