Early hepatocyte DNA synthetic response posthepatectomy is modulated by IL-6 trans-signaling and PI3K/AKT activation.

Journal of Hepatology(2011)

引用 34|浏览15
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摘要
Following PH, IL-6/sIL-6R cooperates with growth factors, through a PI3K/AKT-dependent mechanism to promote entry of hepatocytes into the cell cycle.
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关键词
Liver regeneration,IL-6 trans-signaling,IL-6,sIL-6R,sgp130,HIL-6,PI3K/AKT
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