Inter-reader and intra-reader agreement for grading acute rejection and airway inflammation after lung transplantation, based on the lung rejection study group revised working formulation

The Lung Rejection Study Group standardized grading of acute rejection after transplantation by the degree of perivascular inflammation (A grade). They also emphasized the degree of airway inflammation (B grade), a likely precursor to bronchiolitis obliterans and chronic rejection. We determined the inter-reader and intra-reader agreements for both categories from transbronchial biopsies.