3,4-Dihydro-2H-benzoxazinones are 5-HT1A receptor antagonists with potent 5-HT reuptake inhibitory activity
Peter J. Atkinson,Steven M. Bromidge,Mark S. Duxon,Laramie M. Gaster,Michael S. Hadley,Beverley Hammond,Christopher N. Johnson,Derek N. Middlemiss,Stephanie E. North,Gary W. Price,Harshad K. Rami,Graham J. Riley,Claire M. Scott,Tracey E. Shaw,Kathryn R. Starr,Geoffrey Stemp,Kevin M. Thewlis,David R. Thomas,Mervyn Thompson,Antonio K.K. Vong,Jeannette M. Watson Bioorganic & Medicinal Chemistry Letters(2005)
摘要
The discovery of the potent 5-HT1A receptor antagonist and 5-HT reuptake inhibitor 31 is reported.
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