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黄芩苷在不同溶媒中的稳定性研究

China Pharmacist(2006)

Cited 12|Views16
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Abstract
目的:研究黄芩苷在不同溶媒中的稳定性。方法:采用HPLC法测定黄芩苷的含量。结果:黄芩苷在0.1~50.0μg· ml-1范围内线性关系良好平均回收率为97.6%,RSD=2.0%。黄芩苷在pH=7.4的磷酸盐缓冲液中不稳定。结论:低浓度的黄芩苷在不同pH值溶液中的稳定性差异较大,为透皮扩散研究时pH值和浓度的选择提供了依据。
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Key words
Oil/water detached coefficient,Baicalin,Solvent,Stability
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