颅脑外伤后脑脊液促性腺激素释放激素的含量测定

Chinese Journal of Practical Nervous Diseases(2013)

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Abstract
目的探讨颅脑外伤患者脑脊液中促性腺激素释放激素(GnRH)含量变化及临床意义。方法临床收集130例颅脑外伤患者脑脊液标本为实验组,另选取54例健康者脑脊液标本为对照组。应用放射免疫技术测定患者24h、1周及2周脑脊液中GnRH的含量变化。结果测试发现颅脑外伤后GnRH在脑脊液中的含量明显升高,可能与脑损伤程度关系密切。实验组所有脑脊液标本中GnRH含量显著高于健康对照组(P<0.05)。结论颅脑损伤患者脑脊液中GnRH的含量升高,有助于判定脑损伤程度。
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Key words
Cerebrospinal fluid(CSF),Gonadotropin-releasing hormone(GnRH),Traumatic brair injury
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