Novel flavonol analogues as potential inhibitors of JMJD3 histone demethylase—A study based on molecular modelling

•Epigenetic control of gene expression is maintained by JMJD3.•Earlier reports are available on myricetin as a proven inhibitor of Jmj-C demethylases.•65 analogues of myricetin were identified through a similarity search in ZINC database and screened against JMJD3.•Our findings highlight the 8 most promising analogues of myricetin as possible inhibitors of JMJD3.