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Indanylacetic acids as PPAR-δ activator insulin sensitizers

Philip Wickens,Chengzhi Zhang,Xin Ma,Qian Zhao,John Amatruda,William Bullock,Michael Burns,Louis-David Cantin,Chih-Yuan Chuang,Thomas Claus,Miao Dai,Fernando Dela Cruz,David Dickson,Frederick J. Ehrgott,Dongping Fan,Sarah Heald,Martin Hentemann,Christiana I. Iwuagwu,Jeffrey S. Johnson,Ellalahewage Kumarasinghe,David Ladner,Rico Lavoie,Sidney Liang,James N. Livingston,Derek Lowe,Steve Magnuson,Gretchen Mannelly,Ingo Mugge,Herbert Ogutu,Susan Pleasic-Williams,Robert W. Schoenleber,Jeff Shapiro,Tatiana Shelekhin,Laurel Sweet,Christopher Town,Manami Tsutsumi

Bioorganic & Medicinal Chemistry Letters（2007）

Cited 17|Views35
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Abstract
A novel series of indane acetic acid molecules are insulin sensitizers and have selectivity for PPAR-δ agonist activity over PPAR-α.
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Key words
PPAR,Insulin sensitizer,Indane acetic acids
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