Solid-phase combinatorial synthesis and cytotoxicity of 3-aryl-2,4-quinazolindiones

Hea-Young Park Choo,Mihyun Kim,Sang Kook Lee,Sang Woong Kim,In Kwon Chung

Bioorganic & Medicinal Chemistry（2002）

引用 56|浏览8

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摘要

A series of 3-aryl-2,4-quinazolinediones with various substitution on aromatic rings has been prepared by solid-phase synthesis. Several compounds showed cytotoxicity on human colon carcinoma (Col2) tested by SRB method.

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Microwave-Assisted Synthesis

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