Modification of serum IGF-I, IGFBPs and SHBG levels by different HRT regimens.
Maturitas(2003)
Abstract
The association of cyproterone acetate to oral estradiol determines a significant reduction of IGF-I levels and an increase of SHBG; nevertheless, it does not seem to influence the serum levels of the IGF-I binding proteins. The treatment with oral continuous combined estrogens plus androgenic progestins, at low doses, produces minor, not significant, changes in the circulating levels of IGF-I, SHBG and IGFBPs.
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Key words
IGF-I,SHBG,IGFBPs,hormone replacement therapy (HRT)
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