Synthesis and antienteroviral activity of a series of novel, oxime ether-containing pyridyl imidazolidinones.
Bioorganic & Medicinal Chemistry Letters（2005）
Abstract
A series of pyridyl imidazolidinones were synthesized and their antiviral activity was evaluated in a plaque reduction assay. It was found that the pyridyl imidazolidinone with an ethyl oxime ether functionality, 8b, exhibited extremely high activity against human enterovirus 71.
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Key words
Enterovirus
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