Extrinsic and intrinsic apoptosis pathways in chronic liver diseases

Digestive and Liver Disease(2008)

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摘要
Background. In the liver the apoptotic process appears to be a host defence mechanism against viral infection and carcinogenesis. Two overlapping signalling pathways lead to apoptosis: the extrinsic, cell surface receptors mediated, and the intrinsic mitochondria dysfunction mediated.
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关键词
intrinsic apoptosis pathways,liver
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