NVB联合顺铂治疗蒽环类化疗后的晚期乳腺癌30例疗效分析
Journal of Basic and Clinical Oncology(2006)
Abstract
目的观察去甲长春花碱(Vinorelbine,NVB)联合顺铂(Cisplatin,DDP)治疗用过蒽环类的转移性乳腺癌的疗效及不良反应。方法采用NVB 25 mg/m2,d1,8,DDP 35 mg/m2,d1~3,每3周重复1次。结果有效率为43.3%(13/30),均为PR,主要不良反应为白细胞减少,Ⅳ度发生率为40.1%。结论NVB联合DDP治疗转移性乳腺癌有较好的疗效,且对蒽环类治疗失败的患者亦有较好的疗效,不良反应可耐受。
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Key words
Vinorelbine,Cisplatin,advanced breast cancer
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