BIOACTIVITY OF NICKEL(II) COMPLEX CONTAINING N-GLYCOSIDES DERIVED FROM D-GLUCOSAMINE AND ETHYLENEDIAMINE AGAINST PATHOGENIC YEAST, CANDIDA-ALBICANS

Shigenobu Yano,Sahoko Inoue,Reiko Nouchi,Masako Kato,Takahito Suzuki

BIOLOGICAL & PHARMACEUTICAL BULLETIN（1995）

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摘要

A nickel(II) complex containing N-glycosides derived from the reaction of D-glucosamine (D-GlcN) and ethylenediamine (en) [Ni(D-GlcN-en)(2)]Cl-2 . H2O showed effective antifungal activity against pathogenic yeast, Candida albicans, where the MIC (minimal concentration of inhibition) value of the complex is 0.25 mM.

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关键词

N-GLYCOSIDE NICKEL(II) COMPLEX,AMINO SUGAR,ANTIFUNGAL ACTIVITY,CANDIDA ALBICANS

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