Study of relationship between imaging features of ischemic small vessel disease and vascular cognitive impairment

Objective To explore the relationship between the imaging characteristics of ischemic small vascular disease and vascular dementia.Methods 74 patients with small vessel disease(SVD) according to MRI or CT images were divided into dementia group(40 cases) and control group(34 cases).The patients were evaluated with mini-mental state examination(MMSE) and Montreal cognitive assessment(MoCA) after lacunar infarction(LI) 3 months.Results(1)MoCA score was much lower than MMSE score in dementia group and control group.(2)There were significant deviation in lesions of frontal lobe,temporal lobe,basal ganglia,and thalamus in vascular dementia(VD) group more than control group(P0.05).(3)Smoking,alcohol,white matter lesions(WML),brain atrophy,infarction times(≥ twice),infarction location(bilateral)in VD group were significantly higher than those in control group(P0.05).Conclusions(1)MoCA was more sensitive than MMSE in evaluation of ischemic SVD patients.(2)The lesion location,smoking,alcohol,WML,brain atrophy,infarction times(≥ twice),infarction location(bilateral) were related to VD.