颈椎病中疼痛患者血清细胞因子表达与其疼痛的相关性研究
The Journal of Cervicodynia and Lumbodynia(2013)
Abstract
目的通过测定颈椎病中疼痛患者血清炎性细胞因子的含量及其疼痛的关系,对其病变深入研究。方法选取2012-01-2012-12我院门诊和住院的颈椎病中疼痛患者48例为试验组。颈椎病根据临床症状结合影像学检查确诊。选择成年健康体检者40例为对照组;采用放免法测定血清中白细胞介素6、肿瘤坏死因子α的含量,应用目测类比评分法测定患者疼痛程度。结果试验组血清白细胞介素6、肿瘤坏死因子α、白细胞介素1β含量显著高于对照组(P<0.05),且试验组中重度疼痛组上述血清细胞因子含量亦显著高于轻度疼痛组(P<0.05)。结论颈椎病中疼痛患者血清白细胞介素6、肿瘤坏死因子α、白细胞介素1β明显升高是导致疼痛的因素。
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Key words
cervical spondylosis,cytokine,pain
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