Clinical application of minor agglutination appeared in cross-matching by microtubes-gel test

Objective To find out the clinical value of the minor agglutination appeared in the cross-matching by the microtubes-gel test(MGT) through analyzing the biochemical indicators and the illness course in the patients with minor agglutination.Methods 27 patients with minor agglutination,correct blood grouping in the cross-matching and negative results by MGT in this hospital during 2011 were selected as the test group.Contemporaneous 35 patients with the same illness and the normal results in cross-matching by MGT were selected as the control group and 20 healthy individuals as the healthy control group.Blood urea nitrogen(BUN),creatinine(Cr),C reaction protein(CRP) and B brain natriuretic peptide(BNP) contents were retrospectively analyzed.Complications and the death rate were statistically analyzed.Results 27 case-times of minor agglutination showed pulmonary infection,accounting for 77.8%.The positive rates of BUN,Cr,CRP and BNP in the test group were 85.2%,55.6%,96.3% and 88.9% respectively.Compared with the patient control group and the healthy control group,the differences in these indexes showed statistical significance(P0.05).The average levels of BUN,Cr,CRP and BNP in the test group were(16.55±8.02)mmol/L,(177.7±165.1)μmol/L,(71.54±61.89)mg/L and(864.15±1 162.33)pg/mL.Compared with the patient control group and the healthy control group,the differences except Cr showed statistical significance(P0.05).The death rates in the test group and the patient control group were 66.7% and 14.3% respectively with statistical difference between them(P0.05).Conclusion The minor agglutination appeared in the cross-matching by the microtubes-gel test prompts the severe illness course,which can be used as an index for judging the prognosis of the course.