A Convenient and Efficient Route to 1,4-Bis(heteroaryl)- buta-1,3-diene and 4-Heteroarylbut-1-en-3-yne from 1,4-Dichlorobut-2-yne

CHINESE JOURNAL OF CHEMISTRY(2007)

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Abstract
A convenient and practical route to functionalized conjugated 1,3-enynes and 1,3-dienes is described. 1,4-Bis(heteroaryl)-1,3-diene and 1-heteroarylbut-1-en-3-yne derivatives were prepared from 1,4-dichloro-2-butyne and corresponding N-heteroarenes such as imidazole, pyrrole, pyrazole and indole derivatives in the presence of bases in good to high yields.
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Key words
heterocycle,1,3-diene,1,3-enyne,C-N bond formation
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