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排名必读论文期刊顶会热点AI 简史溯源树小脉星探人才迁徙塔尖人才国防情报追踪开源工具智慧手语
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5-Aminomethyl-1H-benzimidazoles as orally active inhibitors of inducible T-cell kinase (Itk)

Michael P. Winters,Darius J. Robinson,Hnin Hnin Khine,Steven S. Pullen,Joseph R. Woska,Ernest L. Raymond,Rosemarie Sellati,Charles L. Cywin,Roger J. Snow,Mohammed A. Kashem,John P. Wolak,Josephine King,Paul V. Kaplita,Lisa H. Liu,Thomas M. Farrell,Renee DesJarlais,Gregory P. Roth,Hidenori Takahashi,Kevin J. Moriarty

Bioorganic & Medicinal Chemistry Letters（2008）

引用 23|浏览58
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摘要
The SAR of this 5-aminomethyl-benzimidazole class of Itk inhibitors is discussed, along with in vivo efficacy in a mouse model.
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关键词
SAR,Itk inhibitor,Benzimidazole,In vivo mouse model
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