甲瓦龙酸内酯的合成研究
Chemical Industry Times(2009)
Abstract
甲瓦龙酸内酯是重要的医药中间体。以4-氯-2-丁酮为原料,经酯化、Reformatsky反应、水解和环合制备了甲瓦龙酸内酯,该方法具有合成收率高、纯度高的优点,产物经GC-MS确证。
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Key words
mevalonic lactone synthesis Reformatsky reaction
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