Detection of circulating immunocomplexes in patients diagnosed with acute brucellosis

JC Plata,J Leiva,MJ Martínez,J Mendoza,JM Navarro,M de la Rosa Fraile

Serodiagnosis and Immunotherapy in Infectious Disease（1994）

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摘要

The presence of circulating immunocomplexes (ICs) was studied in 57 patients diagnosed with acute brucellosis. Total ICs were detected directly with nephelometry and Brucella-specific ICs by immunoblotting. The frequency of total ICs was 75.4% and Brucella-specific ICs were found in 50.9%. The most frequent protein antigens were those against 66 kDa and 21 kDa. No Brucella-specific ICs were found in sera from any of the control subjects.

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Circulating immunocomplexes,Brucella-specific ICs,immunoblotting,polyethylene glycol

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