Study on the bioassay of Scutellaria processed products.

Objective To establish a dose-response curve and bioassay method of quality evaluation for scutellaria processed products.Method The extract of Scutellaria processed products was prepared,and a standard curve by susceptible strains of the inhibition zone diameter and logarithm of the concentration was established.According to Chinese Pharmacopoeia edition 2010,the content of baicalin was determined and compared with the pharmacopoeia methods.Results There was a good linear relationship between logarithmic dose and response effect when the concentration in the range of 0.204 8-0.976 6 g·mL-1.Bioassay and HPLC results were not consistent completely.Conclusion As a quality control method of Scutellaria processed products,the bioassay is feasible and reasonable.