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联检血清VEGF、CA15-3、TSGF及放射性核素骨扫描对乳腺癌骨转移诊断的临床价值

Journal of Radioimmunology(2011)

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Abstract
目的:探讨了联检血清VEGF、CA15-3、TSGF及放射性核素显像对诊断乳腺癌骨转移的临床价值。方法:应用发光免疫分析技术和酶联法检测了82例乳腺癌患者血清VEGF、CA15-3、TSGF这三种肿瘤标志物,应用SPECT对既有患者进行了骨扫描检测,以明确有无转移。结果:82例乳腺癌患者血清VEGF、CA15-3、TSGF水平均显著地高于正常人组(P≤0.01),32例临床诊断为乳腺癌骨转移组又非常显著地高于正常人组(P≤0.01)。结论:检测血清VEGF、CA15-3、TSGF水平结合全身骨扫描可提高对乳腺癌骨转移诊断的准确性,具有重要的临床价值。
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Key words
breast cancer,whole body bone scan,carbohydrate antigen15-3(CA15-3),vascular endothelium growth factor(VEGF),bone metastasis,tumor special growth factor(TSGF)
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