以前列腺干细胞抗原为靶点的前列腺癌免疫治疗研究进展

Letters in Biotechnology(2012)

Cited 23|Views28
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Abstract
前列腺干细胞抗原(PSCA)为细胞膜表面抗原,在正常前列腺组织中低表达,在雄激素依赖性和非依赖性前列腺癌组织中高表达,有较高的组织特异性,是前列腺癌治疗的理想靶标,近年来以PSCA为靶点的前列腺癌治疗性疫苗的研究已成为热点。我们简要综述以PSCA为靶点治疗前列腺癌的研究进展。
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Key words
prostate stem cell antigen,immunotherapy,prostate cancer
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