千金妇康片对更年期综合征模型大鼠的影响
Qilu Pharmaceutical Affairs（2012）
Abstract
目的 探讨千金妇康片治疗更年期综合征的作用机理.方法 去卵巢法制备大鼠更年期综合征模型,测定模型大鼠血清E2、FSH、LH,下丘脑5-HT、NE、DA的含量变化.结果 千金妇康片能显著增加对模型大鼠血清E2水平(P<0.01),降低血清FSH、LH水平(P<0.01),增加NE含量(P<0.01),增加肾上腺系数(P<0.05),对模型大鼠下丘脑5-HT含量有降低趋势.结论 千金妇康片通过调节血清激素及下丘脑神经递质变化发挥治疗更年期综合征的作用.
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Key words
Monoamine-neurotransmitters level,Qianjin Fukang Pills,Estrogen level,Menopausal syndrome model in rats
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