Synthesis, SAR, and X-ray structure of novel potent DPPIV inhibitors: Oxadiazolyl ketones
Bioorganic & Medicinal Chemistry Letters（2007）
Abstract
Compound 18h showed excellent inhibitory activity against DPPIV, good selectivity over DPPII and DPPVIII, and showed good PK, PD profile.
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Key words
Oxadiazolyl ketones,DPPIV inhibitors
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