头孢唑啉在妇科围术期预防应用的随机对照研究
China Pharmacy(2008)
Abstract
目的:研究头孢唑啉联合甲硝唑在妇科围术期的预防效果。方法:142例择期手术者随机分组,试验组予头孢唑啉和甲硝唑,对照组予青霉素、氨苄青霉素和甲硝唑,比较2组围术期感染情况和药费。结果:清洁、清洁-污染手术2组间感染情况均无显著性差异(P>0.05),期间均未发生药品不良反应,试验组预防用药天数和抗菌药费及住院总药费显著低于对照组(P<0.01)。结论:头孢唑啉联合甲硝唑预防妇科围术期感染安全、有效、经济。
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Key words
Cefazolin,Gynecology,Perioperative period,Prophylaxis
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