Clinical Observation of 60 Cases of Parkinson′s Disease Treated with Chinese medicine Kangchanning

Objective To observe the clinical efficacy of Chinese medicine kangchanning on Parkinson′s disease.Methods 60 cases of Parkinson′s disease were divided randomly into treatment group(30 cases)and control group(28 cases).In treatment group,Chinese medicine kangchanning and madopar were administered.In control group,madopar was only administered.The duration of treatment was 2 months.The Unified Parkinson′s Disease Rating Scale(UPDRS)was used to score the symptoms and physical signs before and after medication in two groups.The incidence of non-motor symptoms of two groups were observed,including insomnia,profuse sweating,mental disturbance,fatigue,unknown pain,cognitive dysfunction,etc.Results Before and after treatment,UPDRS score was much more different in treatment group as compared with control group,indicating significant statistical difference(P0.05).After medication,in treatment group,of non-motor symptoms,the incidences of insomnia,defecation dysfunction,profuse sweating and fatigue were different significantly in statistics as compared with control group;and those of mental disturbance,unknown pain and cognitive dysfunction decreased as compared with control group,but without significant statistical difference.Conclusion Chinese medicine kangchanning can improve apparently not only in the motor symptoms of the patients with Parkinson′s disease but also in many non-motor symptoms such as insomnia,defecation dysfunction,profuse sweating and fatigue.