Prolonged Three Year Survival After Adjuvant Chemotherapy With Uft/Leukovorin For Ii, Iiia And Iiib Diffuse Gastric Cancer

3-Similar measurements were repeated in these patients after being on diet and Thalidomtde for 2 weeks.RESULTS: One female patient and 4 male patients with a mean age of 69 years (61 -77 yrs) lost weight on diet alone from a mean baseline weight of 73.9kg to 72.6kg in two weeks.After being on Thalidomide for 14 days all patients experienced weight gain from a mean weight of 72.6kg to 74.3kg.Similar trend was shown in lean body mass in all these patients.There was an increase in REE in kcal/kg/day in 4 out of 5 patients on Thalidomide therapy.CONCLUSIONS: Thalidomide therapy is effective in causing weight gain mainly in the lean body mass in patients with inoperable oesophageal cancer.Its promising role as an anti-cachectic treatment in cancers needs further evaluation.