Lesões de isquemia-reperfusão em músculos esqueléticos: fisiopatologia e novas tendências de tratamento com ênfase em reperfusão controlada

Abstract Acute arterial embolism ,is the most frequent vascular surgery emergency. Its main causes are embolies and arterial thrombosis. In addition to severe ischemia, reperfusion of the ischemic tissues can cause several complications that may worsen the lesion. Through systemic alterations, the patient might be exposed to a life threatening situation. The objective of this paper is to review the research on pathophysiology, highlighting individual contributions, therapeutic assays and controversy,