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水银不同炮制方法与抗炎镇痛相关性研究

Guiding Journal of Traditional Chinese Medicine and Pharmacy(2012)

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Abstract
目的:研究水银的炮制方法与镇痛、抗炎功效的相关性,确定药物发挥功效的最佳炮制方法。方法:根据水银祛风除湿止痛的功效,选择热板痛证模型、新鲜蛋清所致足趾肿胀的炎症模型,确定药物抗炎、镇痛的最佳炮制方法。结果:热制水银方法炮制明显延长热板刺激小鼠添足潜伏期,提高热板小鼠痛阀值,抗炎作用明显高于其他炮制组。结论:热制水银镇痛、抗炎作用强。
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Key words
Processing methods,Analgesic,Anti-inflammatory,Selecting,Mercury
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