Convenient synthesis of ? benzyl ester

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS(1999)

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摘要
Mesylates or tosylates of delta-hydroxy-L-norvaline esters spontaneously afford L-proline esters upon exposure to aqueous buffer in near quantitative yield. This novel reaction has led to the development of a simple route to optically active proline esters. (C) 1999 Elsevier Science Ltd. All rights reserved.
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