071 Procoralan, an If current inhibitor, improves systolic function and enhances FKBP12 expression after myocardial infarction and 3 weeks of reperfusion in conscious rabbits

Conclusion Heart rate reduction with IVA significantly improves systolic function after 3 weeks of reperfusion. This beneficial effect might result from an adaptation of calcium handling as suggested by the increase in FKBP12 expression.