CIRCULATING VEGF CONCENTRATIONS ARE INDEPENDENTLY PREDICTIVE OF CORONARY ARTERY DISEASE SEVERITY MEASURED BY QUANTITATIVE CORONARY ANGIOGRAPHY IN PATIENTS WITH STABLE ANGINA

VEGF is hypothesized to be implicated in the development and progression of atherosclerotic plaques by promoting intra-plaque vascularisation and hamorrhage. However, clinical data regarding the value of VEGF as a biomarker of atherosclerosis have been contradicting. We sought to evaluate the association between VEGF and the severity of coronary artery disease assessed by quantitative coronary angiography (QCA).