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Improving the Developability Profile of Pyrrolidine Progesterone Receptor Partial Agonists.

Lara S. Kallander,David G. Washburn,Tram H. Hoang,James S. Frazee,Patrick Stoy,Latisha Johnson,Qing Lu,Marlys Hammond,Linda S. Barton,Jaclyn R. Patterson,Leonard M. Azzarano,Rakesh Nagilla,Kevin P. Madauss,Shawn P. Williams,Eugene L. Stewart,Chaya Duraiswami,Eugene T. Grygielko,Xiaoping Xu,Nicholas J. Laping,Jeffrey D. Bray,Scott K. Thompson

Bioorganic & Medicinal Chemistry Letters（2009）

Cited 11|Views75
Key words
Pyrrolidine,Progesterone,Progesterone receptor,Partial agonist,hERG,Rat DMPK,Rat OVX model,Endometriosis
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