Dietary inhibition of experimental atherosclerosis in rabbits by 2-ethyl-n-caproic acid

Four groups of rabbits were fed for 10 weeks on diets composed of rabbit pellets and lard (2.5%) and containing either cholesterol (2 %), 2-ethyl-n-caproic acid (2.5 %), or both. Blood samples obtained at two-week intervals were analyzed for α- and β-lipoprotein lipids; at the end of the experiment, the aortic intima was graded for atheromatous plaques, and aorta and liver lipid contents were determined.