Hormone Replacement Therapy and Breast Cancer Risk in High-Risk Subgroups

Epidemiologie studies have attempted to identify whether certain subgroups of postmenopausal women using hormone replacement therapy (HRT) are more susceptible to the effects of steroids in relation to breast cancer risk. Subgroups of interest include women with a family history of breast cancer, women with a history of benign breast disease (BBD), obese individuals, older hormone users, past users of oral contraceptives (OC), and women who consume alcohol.