Polymer-Supported Bases. 10. Synthesis of Phosphatidylcholines Using Polymer-Supported or Free Acylimidazoles
SYNTHETIC COMMUNICATIONS(2006)
Abstract
Dipalmitoylphosphatidylcholine was synthesized in a good yield by the reaction of L-α-glycerophosphorylcholine with 1-palmitoylimidazole in the presence of DBU. Polymer-supported 1-palmitoylimidazole moiety also could be used as the acylating reagent, though the yield of the choline was moderate.
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Key words
phosphatidylcholines,free acylimidazoles,polymer-supported,polymer-supported
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