B-cell lymphoproliferation in chronic inflammatory rheumatic diseases
NATURE CLINICAL PRACTICE RHEUMATOLOGY(2007)
Abstract
Patients with chronic inflammatory rheumatic diseases, such as primary Sjögren's syndrome, systemic lupus erhythematosus and rheumatoid arthritis, are at higher risk of developing B-cell non-Hodgkin lymphomas compared with the general population. In their Review, Dr Hansen, Dr Lipsky and Dr Dörner discuss the risk of lymphoma, the common and disease-specific mechanisms of B-cell lymphoma development, and the clinical consequences in patients with inflammatory rheumatic diseases.
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Key words
B cells,lymphoma,lymphoproliferation,rheumatic diseases,risk factors
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