Incorporation of fluoroprolines to proctolin: Study on the effect of a fluorine atom toward peptidic conformation
Journal of Fluorine Chemistry(2008)
Abstract
The biologically active pentapeptide, proctolin 1, and its monofluorinated derivatives 2 and 3 at the 4 position of proline were synthesized, and their conformations were analyzed on the basis of their NOESY spectra.
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Key words
Fluorinated amino acid,Peptidic conformations,NOESY spectra
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