Approaches to the stereoselective total synthesis of biologically active natural products

PURE AND APPLIED CHEMISTRY(2005)

引用 6|浏览11
暂无评分
摘要
Total syntheses of epothilone B and pamamycin 607, which feature reactions between functionalized allylstannanes and aldehydes to introduce a (Z)-trisubstituted double-bond and remote stereocenters stereoselectively, are discussed. Recent work concerned with carrying out this chemistry without the use of allylstannanes as starting materials and progress toward a total synthesis of bryostatins are also presented.
更多
查看译文
关键词
biological activity,total synthesis,stereoselectivity
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要