High-performance thin-layer chromatographic method to determine sorption of propofol to infusion containers

A stability-indicating HPTLC method developed for the determination of propofol was used to monitor the effect of different infusion containers on the stability of propofol in 5% glucose. According to the results, the new polypropylene-lined bags and glass bottles can safely be used for administration of propofol by i.v. infusion, but polyvinyl chloride bags are not recommended.