Immune modulation to prevent antibody-mediated rejection after allogeneic hematopoietic stem cell transplantation.

Transplant Immunology(2011)

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摘要
It has been shown that antibodies to donor CD34+/VEGFR-2+ stem cells or antibodies against mismatched HLA are associated with graft rejection after hematopoietic stem cell transplantation (HSCT). CD34/VEGFR-2 positive stem cells have been implicated to play a major role in engraftment after HSCT.
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关键词
Allogeneic stem cell transplantation,Rituximab,Rejection
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